段胜仲-中国科学院大学-UCAS
[中文]
[English]
教育背景
工作经历
教授课程
出版信息
科研活动
基本信息
段胜仲 男 博导 上海交通大学电子邮件： szduan@sibs.ac.cn通信地址： 上海市岳阳路320号新生命大楼A座2122邮政编码： 200031
招生信息
招生专业
071010-生物化学与分子生物学086000-生物与医药
招生方向
核受体与代谢和疾病心血管疾病糖尿病
教育背景
2000-09--2006-04 密歇根大学 博士
工作经历
工作简历
2006-05~2010-10,密歇根大学, 博士后2000-09~2006-04,密歇根大学, 博士
教授课程
营养学
出版信息
发表论文
（1） Mineralocorticoid Receptor Deficiency in Macrophages Inhibits Neointimal Hyperplasia and Suppresses Macrophage Inflammation Through SGK1-AP1/NF-kB pathways., Arterioscler Thromb Vasc Biol., 2016, 通讯作者（2） Thromboxane Governs the Differentiation of Adipose-Derived Stromal Cells Toward Endothelial Cells In Vitro and In Vivo., Circ Res., 2016, 第 4 作者（3） Prognostic Value of Tumor Deposit and Perineural Invasion Status in Colorectal Cancer Patients: a SEER-Based Population Study., Histopathology, 2016, 第 4 作者（4） Impaired Endothelial Repair Capacity of Early Endothelial Progenitor Cells in Hypertensive Patients With Primary Hyperaldosteronemia: Role of 5,6,7,8-Tetrahydrobiopterin Oxidation and Endothelial Nitric Oxide Synthase Uncoupling., Hypertension., 2016, 第 4 作者（5） High salt primes a specific activation state of macrophages, M(Na)., Cell Res., 2015, 通讯作者（6） nhibition of glutathione production induces macrophage CD36 expression and enhances cellular oxLDL uptake., J Biol Chem., 2015, 第 4 作者（7） Bach1 Represses Wnt/β-Catenin Signaling and Angiogenesis., Circ Res., 2015, 第 4 作者（8） Suppression of glioblastoma by targeting the overactivated protein neddylation pathway., Neuro Oncol., 2015, 第 4 作者（9） EP3 receptor deficiency attenuates pulmonary hypertension through suppression of Rho/TGF-β1 signaling., J Clin Invest., 2015, 第 4 作者（10） Genetic targeting of sprouting angiogenesis using Apln-CreER., Nat Commun., 2015, 第 4 作者（11） Neddylation-Cullin 2-RBX1 E3 ligase axis targets tumor suppressor RhoB for degradation in liver cancer., Mol Cell Proteomics., 2015, 第 4 作者（12） Histology subtypes and polyp size are associated with synchronous colorectal carcinoma of colorectal serrated polyps: a study of 499 serrated polyps., Am J Cancer Res., 2015, 第 4 作者（13） Myeloid mineralocorticoid receptor deficiency inhibits aortic constriction-induced cardiac hypertrophy in mice., PLoS One., 2014, 通讯作者（14） Targeting the c-Met/FZD8 signaling axis eliminates patient-derived cancer stem-like cells in head and neck squamous carcinomas., Cancer Res., 2014, 第 3 作者（15） Epicardium-to-fat transition in injured heart., Cell Res., 2014, 第 4 作者（16） Mineralocorticoid receptor: a critical player in vascular remodeling., Sci China Life Sci., 2014, 通讯作者（17） Rosiglitazone Causes Cardiotoxicity via Peroxisome Proliferator-Activated Receptor γ-Independent Mitochondrial Oxidative Stress in Mouse Hearts., Toxicol Sci., 2014, 第 4 作者（18） Smooth muscle protein 22 alpha-Cre is expressed in myeloid cells in mice., Biochem Biophys Res Commun., 2012, 通讯作者（19） Effects of PPARs Agonists on Cardiac Metabolism in Littermate and Cardiomyocyte-Specific PPAR-γ-Knockout (CM-PGKO) Mice., PLoS One., 2012, 第 4 作者（20） Myeloid-Specific Deletion of the Mineralocorticoid Receptor Reduces Infarct Volume and Alters Inflammation During Focal Cerebral Ischemia., Stroke, 2011, 第 3 作者（21） Role of PKCζ translocation in the development of type 2 diabetes in rats following continuous glucose infusion., Diabetes Metab Res Rev., 2010, 通讯作者（22） Sex dimorphic actions of rosiglitazone in generalised peroxisome proliferator-activated receptor-gamma (PPAR-gamma)-deficient mice., Diabetologia., 2010, 第 1 作者（23） Myeloid mineralocorticoid receptor controls macrophage polarization and cardiovascular hypertrophy and remodeling in mice., J Clin Invest., 2010, 通讯作者（24） A New Connection: Myeloid Mineralocorticoid Receptor and Cardiovascular Disease. , NAJMS., 2010, 通讯作者（25） PPARs: the vasculature, inflammation and hypertension., Curr Opin Nephrol Hypertens., 2009, 第 1 作者（26） Go controls the hyperpolarization-activated current, If in ES cell-derived cardiocytes., Am J Physiol Heart and Circulatory Physiol., 2008, 第 2 作者（27） PPAR-g mediated effects in the vasculature. , Circ Res., 2008, 第 1 作者（28） PPAR-g in the cardiovascular system., PPAR Res., 2008, 第 1 作者（29） In vivo and in vitro studies of a functional peroxisome proliferator-activated receptor gamma response element in the mouse PDX-1 promoter., J Biol Chem., 2008, 第 4 作者（30） Hypotension, lipodystrophy, and insulin resistance in generalized PPAR-g-deficient mice rescued from embryonic lethality., J Clin Invest, 2007, 第 1 作者（31） Go but not Gi2 or Gi3 is required for muscarinic regulation of heart rate and heart rate variability in mice. , Biochem Biophys Res Commun. , 2007, 第 1 作者（32） PPAR-g knockout in pancreatic epithelial cells abolishes the inhibitory effect of Rosiglitazone on cerulein-induced acute pancreatitis., Am J Physiol Gastrointest Liver Physiol., 2007, 第 2 作者（33） Direct monitoring pressure overload predicts cardiac hypertrophy in mice. , Physiological Measurement. , 2007, 第 1 作者（34） Cardiomyocyte-specific knockout and agonist of peroxisome proliferator-activated receptor-g both induce cardiac hypertrophy in mice., Circ Res, 2005, 第 1 作者
科研活动
科研项目
（ 1 ）&nbsp核受体MR的阻断和PPARg的激活在心肌梗死与心肌肥厚中的各自以及协同作用, 负责人, 国家任务, 2014-01--2017-12（ 2 ）&nbsp盐皮质激素受体调控内膜新生和血管重构, 负责人, 国家任务, 2014-01--2016-12（ 3 ）&nbspT细胞盐皮质激素受体对血压的调控作用和机制研究, 负责人, 国家任务, 2017-01--2020-12（ 4 ）&nbsp构建盐皮质激素受体基因敲入小鼠用于心血管疾病研究, 负责人, 地方任务, 2015-07--2018-09
参与会议
（1）An MR/ER/HGF/MET axis conveys signaling from macrophages to hepatocytes in hepatic steatosis and insulin resistance. Shengzhong Duan 2015-11-08（2）High salt primes a specific activation state of macrophages, M(Na). Shengzhong Duan 2015-06-04（3）Deletion of myeloid mineralocorticoid receptor inhibits neointima formation by suppression of macrophage accumulation and inflammatory response and interactions with other vascular cells. Shengzhong Duan 2014-10-25
2013 中国科学院大学，网络信息中心.