刘爱骅-中国科学院大学-UCAS


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刘爱骅-中国科学院大学-UCAS
[中文]
[English]
招生信息
教育背景
工作经历
专利与奖励
出版信息
科研活动
指导学生
研究所个人主页
团队主页
基本信息
刘爱骅 男 博导 青岛生物能源与过程研究所 电子邮件:liuah@qibebt.ac.cn 通信地址:青岛市崂山区松岭路189号 36号信箱 邮政编码:266101
招生信息
招生专业
071010-生物化学与分子生物学070302-分析化学071020-生物技术与医药
招生方向
生物传感器,生物芯片, 生物大分子可控自组装及仿生 生物燃料电池 单分子检测技术
教育背景
2000-10--2004-03 日本东北大学 博士 1990-09--1993-07 厦门大学 硕士 1984-09--1988-07 吉首大学 学士
学历
-- 研究生
学位
-- 博士
工作经历
工作简历
2010-05--今 中科院青岛生物能源与过程研究所 研究员、团队负责人 2009-10--2010-05 美国德克萨斯大学 博士后研究员 2007-05--2009-10 美国俄克拉荷马大学 博士后研究员 2006-05--2007-04 美国密歇根州立大学 助理研究员 2004-04--2006-03 日本产业综合技术研究所 日本学术振兴会特别研究员 1993-08--1997-08 华南理工大学 助教、讲师
社会兼职
2009-08--今 Frontiers in Bioscience,Mangaging Editor
专利与奖励
奖励信息
(1) 入选世界名人录(Marquis Who's Who in the world),其他级,2010 (2) 中国科学院“%%%%”,院级级,2009 (3) Biosensors & Bioelectronics 和Elsevier年度最佳审稿人,其他级,2007 (4) 日本学术振兴会特别研究员奖学金,其他级,2004 (5) 日本国际教育协会赏,其他级,2003 (6) 日本东北开发记念财团赏,其他级,2003
专利成果
(1) 一种从李氏木酶中分离多糖水解酶的方法,发明,2012,第1作者,专利号:201210052751.9 (2) 一种具有高稳定性和高特异性的葡萄糖脱氢酶细菌表面展示系统及其制备和应用,发明,2013,第1作者,专利号:20130152468.8 (3) 一种基于冰核蛋白的木糖脱氢酶细菌表面展示系统及其应用,发明,2013,第1作者,专利号:201210007398.2 (4) 一种多肽及其应用和将多肽固定到固相界面的方法,发明,2014,第1作者,专利号:201410038545.1 (5) 一种仿过氧化物酶及其应用,发明,2014,第1作者,专利号:201410669091.8 (6) 一种定量检测L-半胱氨酸的方法,发明,2014,第1作者,专利号:201410714046.X (7) 一种利用表面展示谷氨酸脱氢酶的全细胞测定L-谷氨酸含量的方法,发明,2014,第1作者,专利号:201410598809.9 (8) 一种顺序酶表面共展示系统及其应用,发明,2014,第1作者,专利号:201410616804.4
出版信息
发表论文
(1) Amperometric L-glutamate biosensor based on bacterial cell-surface displayed glutamate dehydrogenase,Analytica Chimica Acta,2015,通讯作者 (2) Au@Ag heterogeneous nanorods as nanozyme interfaces with peroxidase-like activity and their application for one-pot analysis of glucose at nearly neutral pH,ACS Applied Materials and Interfaces,2015,通讯作者 (3) Bacterial cell-surface displaying of thermo-tolerant glutamate dehydrogenase and its application in L-glutamate assay,Enzyme and Microbial Technology,2015,通讯作者 (4) Microbial surface displayed enzymes based biofuel cell utilizing degradation products of lignocellulosic biomass for direct electrical energy,Bioresource Technology,2015,通讯作者 (5) V2O3-ordered mesoporous carbon composite with novel peroxidase-like activity towards glucose colorimetric assay,Nanoscale,2015,通讯作者 (6) Novel glucose sensor with Au@Ag heterogeneous nanorods based on electrocatalytic reduction of hydrogen peroxide at negative potential,Journal of Electroanalytical Chemistry,2015,通讯作者 (7) Leaf-templated synthesis of 3D hierarchical porous cobalt oxide nanostructure as direct electrochemical biosensing interface with enhanced electrocatalysis,Biosensors and Bioelectronics,2015,通讯作者 (8) Biofuel cell based self-powered sensing platform for L-cysteine detection,Analytical Chemistry,2015,通讯作者 (9) Cell surface display of organophosphorus hydrolase for sensitive spectrophotometric detection of p-nitrophenol substituted organophosphates,Enzyme and Microbial Technology ,2014,通讯作者 (10) Peptide Microarray with Ligands at High Density Based on Symmetrical Carrier Landscape Phage for Detection of Cellulase,Analytical Chemistry ,2014,通讯作者 (11) Enhanced Performance of Glucose/O2 Biofuel Cell Assembled with Laccase-Covalently Immobilized Three-Dimensional Macroporous Gold Film Based Biocathode,Analytical Chemistry ,2014,通讯作者 (12) Specific probe selection from landscape phage display library and its application in enzyme-linked immunosorbent assay of free prostate-specific antigen,Analytical Chemsitry,2014,通讯作者 (13) Sensitive electrochemical microbial biosensor for p-nitrophenylorganophosphates based on electrode modified with cell surface-displayed organophosphorus hydrolase and ordered mesopore carbons,Biosensors and Bioelectronics,2014,通讯作者 (14) Ultrasensitive Electrochemical Sensor for p-Nitrophenyl Organophosphates Based on Ordered Mesoporous Carbons at Low Potential without Deoxygenization,Analytica Chimica Acta ,2014,通讯作者 (15) Substituent effect on the oxidation peak potentials of phenol derivatives at ordered mesoporous carbons modified electrode and its application in determination of acidity coefficients (pKa),Electrochimica Acta,2014,通讯作者 (16) Specific ligands for classical swine fever virus screened from landscape phage display library,Antiviral Research,2014,通讯作者 (17) Porous gold cluster film prepared from Au@BSA microspheres for electrochemical nonenzymatic glucose sensor,Electrochimica Acta,2014,通讯作者 (18) Co-immobilization of glucoamylase and glucose oxidase for electrochemical sequential enzyme electrode for starch biosensor and biofuel cell,Biosensors and Bioelectronics,2014,通讯作者 (19) Bio-mimetic Nanostructure Self-assembled from Au@Ag Heterogeneous Nanorods and Phage Fusion Proteins for Targeted Tumor Optical Detection and Photothermal Therapy,Scientific Reports,2014,通讯作者 (20) Co-immobilization of glucose oxidase and xylose dehydrogenase displayed whole cell on multiwalled carbon nanotube nanocomposite films modified electrode for simultaneous voltammetric detection of D-glucose and D-xylose,Biosensors and Bioelectronics,2013,通讯作者 (21) Direct energy conversion from xylose using xylose dehydrogenase surface displayed bacteria based enzymatic biofuel cell,Biosensors and Bioelectronics,2013,通讯作者 (22) Microbial surface display of glucose dehydrogenase for amperometric D-glucose biosensor,Biosensors and Bioelectronics,2013,通讯作者 (23) Simultaneous voltammetric determination of nitrophenol isomers at ordered mesoporous carbon modified electrode,Electrochimica Acta,2013,通讯作者 (24) Yeast surface displaying glucose oxidase as whole-cell biocatalyst: Construction, characterization and its electrochemical glucose sensing application,Analytical Chemistry,2013,通讯作者 (25) Simultaneously improving stability and specificity of cell surface displayed glucose dehydrogenase mutants to construct whole-cell biocatalyst for glucose biosensor application,Bioresource Technology,2013,通讯作者 (26) Phagemid vectors for phage display: Properties, characteristics and construction,Journal of Molecular Biology ,2012,通讯作者 (27) Construction of xylose dehydrogenase displayed on the surface of bacteria using ice nucleation protein for sensitive D-xylose detection,Analytical Chemistry,2012,通讯作者 (28) A selective and sensitive D-xylose electrochemical biosensor based on xylose dehydrogenase displayed on the surface of bacteria and multi-walled carbon nanotubes modified electrode,Biosensors and Bioelectronics ,2012,通讯作者 (29) Nanoporous PdCu alloy with enhanced electrocatalytic performance,Electrochemistry Communications,2011,第2作者 (30) A three-dimensional hierarchical nanoporous PdCu alloy for enhanced electrocatalysis and biosensing,Analytica Chimica Acta ,2011,第1作者 (31) Unzipping of double-stranded DNA in engineered α-hemolysin pores,The Journal of Physical Chemistry Letters ,2011,第1作者 (32) Nanoporous PtAg and PtCu alloys with hollow ligaments for enhanced electrocatalysis and glucose biosensing,Biosensors and Bioelectronics,2011,第4作者 (33) Development of highly fluorescent silica nanoparticles chemically doped with organic dye for sensitive DNA microarray detection,Analytical and Bioanalytical Chemistry,2011,通讯作者 (34) Stochastic nanopore sensors for the detection of terrorist agents: current status and challenges,Analytica Chimica Acta ,2010,第1作者 (35) Virus-based chemical and biological sensing,Angewandte Chemie International Edition ,2009,第2作者 (36) Nanocomposite films layer-by-layer assembled from genetically engineered filamentous viruses and gold nanoparticles: nanoarchitecture- and humidity-tunable surface plasmon resonance spectra,Advanced Materials,2009,第1作者 (37) Drug effects on the electrochemical detection of norepinephrine with carbon fiber and diamond microelectrodes,Journal of Electroanalytical Chemistry ,2009,第3作者 (38) Towards development of chemosensors and biosensors with metal-oxide based nanowires or nanotubes,Biosensors and Bioelectronics,2008,通讯作者 (39) Diamond microelectrodes for in vitro electroanalytical measurements,Analyst,2008,第5作者 (40) Switchable titanate-nanotube electrode sensitive to nitrate,Applied Physics Letters,2007,通讯作者 (41) Simultaneous voltammetric detection of dopamine and uric acid at their physiological level in the presence of ascorbic acid using poly(acrylic acid)-multiwalled carbon-nanotube composite-covered glassy-carbon electrode,Biosensors and Bioelectronics ,2007,第1作者 (42) Vanadium-oxide nanotubes: synthesis and template-related electrochemical properties,Electrochemistry Communications,2007,第1作者 (43) Biosensing properties of titanate-nanotube film: selective detection of dopamine in the presence of ascorbate and uric acid,Advanced Functional Materials ,2006,第1作者 (44) Effect of solution pH and ionic strength on the stability of poly(acrylic acid)-encapsulated multi-walled carbon nanotubes aqueous dispersion and its application for NADH sensor,Biosensors and Bioelectronics,2006,第1作者 (45) Poly(acrylic acid)-wrapped multi-walled carbon nanotubes complex solubilization in water: definitive spectroscopic properties,Nanotechnology,2006,第1作者 (46) Multilayered mesoporous titanate nanocomposite film: fabrication by layer-by-layer self-assembly and its electrochemical properties with H+ intercalation,Electrochemistry Communications ,2006,第1作者 (47) Multilayer assembly of calf thymus DNA and poly(4-vinylpyridine) (PVP) derivative bearing [Os(bpy)2Cl]2+: redox behavior within DNA film,Bioelectrochemistry,2005,通讯作者 (48) Amperometric biosensor based on tyrosinase-conjugated polysaccharide hybrid film: selective determination of nanomolar neurotransmitters metabolite of 3,4-dihydroxyphenylacetic acid (DOPAC) in biological fluid,Biosensors and Bioelectronics ,2005,第1作者 (49) Electrochemical investigation of the permselectivity of a novel positively-charged sol-gel silicate prepared from tetraethyloxysilane and N-octadecyldimethyl- [3-(trimethoxysilyl)propyl]ammonium chloride,Electrochemistry Communications ,2005,第1作者 (50) Direct electrochemistry of myoglobin in titanate nanotubes film,Analytical Chemistry ,2005,第1作者 (51) Ferrocene-containing polyelectrolyte multilayer film-covered electrodes: electrocatalytic determination of ascorbic acid and use of inner blocking layers to improve the upper detection limit of the electrodes,Analytical and Bioanalytical Chemistry,2004,通讯作者 (52) Use of polymeric indicator for electrochemical DNA sensor: poly(4-vinylpyridine) derivative bearing [Os(5,6 dimethyl-1,10-phenanthroline)2Cl]2+,Analytical Chemistry ,2004,第1作者 (53) Polyelectrolyte multilayer films containing ferrocene: effects of polyelectrolyte type and ferrocene contents in the film on the redox properties,Electroanalysis,2003,第1作者 (54) Ferrocene-containing polyelectrolyte multilayer films: effects of electrochemically inactive surface layers on the redox properties,Langmuir,2003,第1作者
发表著作
(1) 石墨烯,碳纳米管和纳米结构:技术和应用,Applications of Carbon Nanotubes for Biosensing and Nanomedicine, In Graphene, Carbon Nanotubes, and Nanostructures: Techniques and Applications, CRC Press, USA,2013-02,第1作者 (2) 纳米电子学:纳米线、分子电子学和纳米器件,Nanoelectronics: Nanowires, Molecular Electronics, and Nano-devices,McGraw Hill Publisher, USA,2010-08,第1作者
科研活动
科研项目
(1) 抗逆性好、特异、高效价抗体替代物的筛选及其在新型无标记肿瘤标志物电化学阻抗免疫传感器中的应用研究,主持,国家级,2016-01--2018-12 (2) 生物能源过程的多尺度方法学平台-靶向配体筛选平台,主持,研究所(学校)级,2013-05--2015-12 (3) 金纳米结构/特异性配体自组装病毒样聚集体的构筑、表面等离子共振光谱及其肿瘤靶向、光热疗法原理研究,主持,国家级,2013-01--2015-12 (4) 基于酵母表面酶共展示全细胞的新型电化学顺序酶生物传感器的构筑研究,主持,国家级,2013-01--2016-12 (5) 基于风景噬菌体文库的猪瘟病毒配体的高通量筛选,主持,部委级,2012-01--2013-12 (6) 木质纤维素发酵转化燃料乙醇过程中木糖的灵敏、快速、实时检测技术研究,主持,院级级,2011-01--2011-12 (7) 基于丝状噬菌体展示技术的基础研究,主持,研究所(学校)级,2011-01--2013-12 (8) 基于丝状病毒和纳米技术的新型蛋白质芯片的研发,主持,院级级,2010-01--2013-12
参与会议
(1) Fluorescent dye-chemically-doped silica nanostructures for sensitive DNA microarray,2013-06,Aihua Liu (2) Bacterial surface displaying of enzymes as plotforms for biosensing,第十一届全国分析化学学术年会,2012-10,Aihua Liu (3) Nanostructures self-assembled from virus and their application in biosensing,中国化学会第二十八届学术年会,2012-04,Aihua Liu (4) Development of highly fluorescent silica nanoparticles for sensitive gene microarray detection,2011-08,Aihua Liu (5) Single Molecule Sensing with Protein Nanopore,第三届全国生命分析化学学术报告与研讨会,2010-08,刘爱骅 (6) Single Molecule Stochastic Sensing with Protein Nanopore,2010-07,Aihua Liu
指导学生
已指导学生殷龙 硕士研究生 430139-生物工程 祁环 博士研究生 071010-生物化学与分子生物学 唐湘江 硕士研究生 071010-生物化学与分子生物学 现指导学生王菲 博士研究生 071010-生物化学与分子生物学 范树芹 硕士研究生 071010-生物化学与分子生物学 韩磊 博士研究生 081701-化学工程 刘培 博士研究生 071010-生物化学与分子生物学 梁波 博士研究生 081701-化学工程
研究所个人主页
研究所个人主页链接
团队主页
生物传感技术团队主页链接
2013 中国科学院大学,网络信息中心.